Feasibility and Safety of Dabigatran Versus Warfarin for Periprocedural Anticoagulation in Patients Undergoing Radiofrequency Ablation for Atrial Fibrillation
نویسنده
چکیده
Dhanunjaya Lakkireddy, MD,* Yeruva Madhu Reddy, MD,* Luigi Di Biase, MD, PHD,†‡§ Subba Reddy Vanga, MD,* Pasquale Santangeli, MD,† Vijay Swarup, MD, Rhea Pimentel, MD,* Moussa C. Mansour, MD,¶ Andre D’Avila, MD, PHD,# Javier E. Sanchez, MD,† J. David Burkhardt, MD,† Fadi Chalhoub, MD,¶ Prasant Mohanty, MBBS, MPH,† James Coffey, MD,# Naushad Shaik, MD,** George Monir, MD,†† Vivek Y. Reddy, MD,# Jeremy Ruskin, MD,¶ Andrea Natale, MD†§‡‡ Kansas City, Kansas; Austin, Texas; Foggia, Italy; Phoenix, Arizona; Boston, Massachusetts; New York, New York; Kissimmee and Orlando, Florida; and San Francisco, California
منابع مشابه
Effect of Oral Anticoagulant Therapy on Coagulation Activity and Inflammatory Markers in Patients with Atrial Fibrillation Undergoing Ablation: A Randomized Comparison between Dabigatran and Warfarin
Atrial fibrillation (AF) is associated with inflammatory and hypercoagulability state. Previous studies evaluated the safety and efficacy of dabigatran and warfarin in prevention of thrombothic complications. This study was intended to assess the influence of these drugs on hemostatic and inflammatory markers among patient underwent pulmonary vein ablation. A total of 100 patients with AF w...
متن کاملEffect of Oral Anticoagulant Therapy on Coagulation Activity and Inflammatory Markers in Patients with Atrial Fibrillation Undergoing Ablation: A Randomized Comparison between Dabigatran and Warfarin
Atrial fibrillation (AF) is associated with inflammatory and hypercoagulability state. Previous studies evaluated the safety and efficacy of dabigatran and warfarin in prevention of thrombothic complications. This study was intended to assess the influence of these drugs on hemostatic and inflammatory markers among patient underwent pulmonary vein ablation. A total of 100 patients with AF w...
متن کاملUse of dabigatran for periprocedural anticoagulation in patients undergoing catheter ablation for atrial fibrillation.
BACKGROUND Pulmonary vein isolation (PVI) for atrial fibrillation is associated with a transient increased risk of thromboembolic and hemorrhagic events. We hypothesized that dabigatran can be safely used as an alternative to continuous warfarin for the periprocedural anticoagulation in PVI. METHODS AND RESULTS A total of 999 consecutive patients undergoing PVI were included; 376 patients wer...
متن کاملHow to Use Novel Oral Anticoagulants during the Periprocedural Period of Atrial Fibrillation Ablation
Heparin bridging used to be a mainstream periprocedural anticoagulation strategy with warfarin at the dawn of catheter ablation of atrial fibrillation (AF). However, that was replaced by an uninterrupted warfarin strategy, because it was found to be more convenient and even safer [1]. This new strategy then reduced any cause for concern with regard to periprocedural hemorrhagic and thromboembol...
متن کاملSafety and efficacy of dabigatran versus warfarin in patients undergoing catheter ablation of atrial fibrillation: a systematic review and meta-analysis
BACKGROUND Dabigatran etexilate, a new thrombin inhibitor, has been shown to be comparable to warfarin in patients with atrial fibrillation (AF). However, there is a limited body of evidence on the efficacy and safety of using dabigatran among patients undergoing AF catheter ablation. OBJECTIVE A random effects meta-analysis was performed of controlled trials comparing dabigatran and warfarin...
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